ONGOING, PLANNED AND COMPLETED CLINICAL TRIALS.
A Clinical Study to Determine the Facial Skin Benefits of a Periodic Fasting-Mimicking Diet.
Dallas Research Center. Richardson, TX
Effects of Fast Bar on Physiological Fasting - Fast Bar (NCT04499599). L-Nutra, Los Angeles.
PUBLISHED Huang, A. W. Nutrients (2020)
Effects of Fast Bar on Intermittent Fasting - FastBar2 (NCT04790552). L-Nutra, Los Angeles.
Effects of Fast Bar on Physiological Fasting - Fast Drink (NCT04499599). L-Nutra, Los Angeles.
Effects of 1-Day FMD on Intermittent Fasting (Internal Only). L-Nutra, Los Angeles
Glycemic Index Determination of Fast Bar Honey and Nuts. Inquis.
Overweight/Obesity-Associated Olfact Deficit And Fmd. ITER Center for Balance and Rehabilitation Research (ICBRR), Department of Clinical Sciences and Translational Medicine - ENT Unit, University of Rome Tor Vergata.
Phase I, Pilot, Randomized, Placebo-Controlled Study To Evaluate The Efficacy And Safety Of Promet, A Fasting-Mimicking Diet, On Inflammatory (FMDiCMP Study) Cardiomyopathy. (DRKS00019898) Heart Failure and Cardiomyopathies, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin.
Evaluation of a Fasting Mimicking Diet and the Effect on Endothelial Function, Body Composition and Vascular Markers. (NCT04150159) Hypertension Institute (HI) of Nashville, and USC (University of Southern California).
Clinical Feasibility And Efficacy Of Intermittent Use Of A Fasting Mimicking Diet in The Treatment Of Type 2 Diabetes Fasting in Diabetes Treatment (FIT) study. (NCT03811587). Leiden University Medical Centre, The Netherlands.
PUBLISHED Van den Burg E et al. BMC Endocrine Disorders. (2020)
Chronic Fasting And The Late Complications Of Diabetes: A Prospective Exploratory Randomized Controlled Study In Patients With Diabetes Mellitus Type 2. (DRKS00014287) Department of Endocrinology and Clinical Chemistry (Internal Medicine I), University Hospital Heidelberg, Heidelberg, Germany.
Dietary Interventions To Improve The Microvascular Health In South Asian Patients With Early Diabetic Nephropathy (Glycotreat Study) (NCT03889236). Leiden University Medical Centre, The Netherlands.
Primitive Glomerulonephritis And Chronic Kidney Disease In Conservative Therapy With EGFR ≤ 60 ML/MIN (3 STAGE KDOQI) Sapienza University, Rome, Italy.
Effect of a Periodic Fasting-mimicking Diet on Risk Factors for Metabolic Syndrome and Age-related Diseases. University of Southern California. (NCT02158897)
PUBLISHED Brandhorst S et al. Cell. (2015).
PUBLISHED Wei M et al. Sci Transl Med. (2017)
Fasting And Cancer Treatment In Humans: A Case Series Report. University of Southern California, Los Angeles.
PUBLISHED Safdie, Fernando M et al. Aging. (2009)
The Effects Of Short-Term Fasting On Tolerance To (Neo) Adjuvant Chemotherapy In HER2-Negative Breast Cancer Patients: A Randomized Pilot Study (NCT01304251). Leiden, The Netherlands.
0S-08-09 Short-Term Fasting Prior To Platinum-Based Chemotherapy: Feasibility and Impact on Toxicity (NCT00936364). University Of Southern California, Los Angeles, in collaboration with Norris Cancer Center.
PUBLISHED Dorff, T. B. et al. BMC Cancer (2016)
Short-Term Fasting During Chemotherapy In Patients With Gynecological Cancer- A Randomized Controlled Cross-Over Trial (Fit) (NCT01954836). Charité University, Berlin, Germany.
Impact Of Dietary Intervention On Tumor Immunity: The DigesT Trial (DigesT) (NCT03454282) Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
Exploiting Metformin Plus/Minus Cyclic Fasting Mimicking Diet (FMD) to Improve the Efficacy of Platinum-pemetrexed Chemotherapy in Advanced LKB1-inactive Lung Adenocarcinoma: the FAME Trial. (NCT03709147) Fondazione IRCCS Istituto Nazionale dei Tumori, Milano.
PUBLISHED Vernieri C et al. Clin Lung Cancer. (2019)
0S-10-3 A Randomized, Phase Ii Clinical Trial Of A Controlled Diet Prior To Selected Chemotherapy Treatment In Breast And Prostate Cancer, To Evaluate The Impact On Toxicity And Efficacy. (NCT01802346) USC in collaboration with Norris Cancer Center and LAC+USC.
BRCA Main Home Nutritional Intervention-Random Study (NCT03570125). University Hospital, “Policlinico Paolo Giaccone” of Palermo, Italy.
Fasting-Mimicking Diet In Patients Receiving Chemo-Immunotherapy For Treatment Of Metastatic Non-Small Cell Lung Cancer. (NCT03700437) Eskenazi Hospital, Indiana University Melvin and Bren Simon Cancer Center.
Safety, Feasibility And Metabolic Effects Of The Fasting Mimicking Diet (FMD) In Cancer Patients (NCT03340935) Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
PUBLISHED Vernieri et al. Cancer Discovery (2021)
PUBLISHED Caffa et al. Nature Communications (2020)
Dietary Restriction As An Adjunct Neoadjuvant Chemotherapy For Her2 Negative Breast Cancer (DIRECT) (NCT02126449). Quality of life and illness perceptions in patients with breast cancer using a fasting mimicking diet as an adjunct to neoadjuvant chemotherapy in the phase 2 DIRECT trial (NCT02126449). Leiden University Medical Center, Leiden, The Netherlands.
PUBLISHED de Groot et al. Nature Communications (2020)
PUBLISHED Lugtenberg et al. Breast Cancer Res Treat. (2021)
Phase II Study Of A Diet That Simulates Fasting In Patients Undergoing Cancer Treatment. (NCT03595540) University of Genova, Italy.
PUBLISHED Caffa, I. et al. Nature. (2020)
PUBLISHED Valdemarin, F. et al. Cancers. (2021)
Fasting And Nutritional Therapy In Patients With Advanced Metastatic Prostate Cancer (NCT02710721). Charité University, Berlin, Germany.
PCI.GC.002: A Prospective Pilot Cohort Study of Patients with a Known Diagnosis of Cancer, to Document its Metabolic Effects, including Cancer Fatigue, and Metabolic Syndrome, as well as Lifestyle Changes in the Clinic. (NCT04292041). Prostate Cancer Institute, Galway Clinic and National University of Galway (NUIG), Ireland.
The Influence of a Fasting Mimicking Diet on Ulcerative Colitis. (NCT03615690) Division of Gastroenterology & Hepatology Stanford University School of Medicine.
Effects of an Intermittent Reduced Calorie Diet on Crohn's Disease. (NCT04147585) Division of Gastroenterology & Hepatology Stanford University School of Medicine.
A Fasting Mimicking Diet on Ulcerative Colitis Patients Undergoing Tofacitinib Induction. (NCT04505410) University of Miami. Collaboration with Pfizer.
A Run-In Study On The Safety And Tolerability Of A Fasting Mimicking Diet In Relapsing Remitting Multiple Sclerosis Treated With Interferon Beta 1a (Fast-MS Run-In Study). Clinica Neurologica, Ospedale Policlinico S. Martino, Genova, Italy.
Randomized Phase I / II Study Of A Hypoproteic Diet In Patients With Cognitive Impairment. Genova, Italy, University of Genova.
A Randomised Controlled Pilot Study to Compare the Effects of Prolonged Fasting and Ketogenic Low Glycemic Load Treatment on Health Related Quality of Life in Relapsing-remitting Multiple Sclerosis (IGEL). Charité University, Berlin, Germany. (NCT01538355).
PUBLISHED Choi, Y., et al. Cell Reports. (2016)
A Randomized-Controlled Pilot Study To Evaluate The Efficacy Of A Fasting Mimicking Diet Added To Functional Therapy For Depression (NCT04050475) Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo.
PUBLISHED Maniaci G. et al. J Clin Psychol. (2020)
Randomized Phase I/II Study on FMD for the Stimulation of the Anti-Influenza Immunity in the Pre-Fragile Elderly Subject. Policlinico San Martino Genova.
The effect of a Fasting MimickINg Diet on the immune system: an exploratory study (FIND-Study). (NCT04833439). Leiden University Medical Center, The Netherlands.
Pilot Study on the Effects of Fasting Mimicking Diet (FMD) in Women with polycystic Ovary Syndrome (PCOS). University of Salento, Lecce, Italy
Effects Of Fasting-Mimicking Diet On Central And Peripheral Components Of Fatigue, Muscular Resistance. University of Verona, Italy.
PUBLISHED Nardon M. et al. Eur J Appl Physiol. (2022)